International Senior Professional Institute

Immunology Symposium Basel (ISB) 2011

“Immune Responses and Autoimmunity”

Date: Thursday-Friday, 9th -10th June, 2011

Venue: Anatomie Hörsal 230, Institute of Anatomy, University of Basel, Pestalozzistrasse 20, CH-4056 Basel, Switzerland

Organization: ISPI e.V. (International Senior Professional Institute)

Organizers: Una Chen (Giessen, Germany); Antonius Rolink (Basel, Switzerland); Olli Lassila (Turku, Finland); Sabine Mai (Winnipeg, Canada); Hajime Karasuyama (Tokyo, Japan); and Tilman Borggrefe (Freiburg, Germany)
Speakers & Chairpersons:                                                  (ABC family order): Claudia Berek (Berlin, Germany); Bjarne Bogen (Oslo, Norway); Tilman Borggrefe (Freiburg, Germany); Una Chen (Giessen, Germany); Martin Flajnik (Maryland, USA); Donald Gerson (Ontario, Canada); Ulla Günthert (Basel, Switzerland); Rolf Jessberger (Dresden, Germany); Harald Kropshofer (Basel, Switzerland); Antonio Lanzavecchia (Bellinzona, Switzerland); Marinus Lamers (Freiburg, Germany); Olli Lassila (Turku, Finland); Dieter Naeher (Basel, Switzerland); Hans-George Rammensee (Tübingen, Germany); Antonius Rolink (Basel, Switzerland); Mariolina Salio (Oxford, UK); Federica Sallusto (Bellinzona, Switzerland ); Nobuo Sakaguchi (Kumamoto, Japan); Charles Sidman (Bar Harbor, USA); Alan Tyndall (Basel, Switzerland); Dominic van Essen (Freiburg, Germany); Harald von Boehmer (Boston, USA); Matthias Wabl (San Francisco, USA); Andreas Ziegler (Berlin, Germany) and more (Gennaro De Libero* (Basel, Switzerland); Lucia Mori* (Basel, Switzerland); Jean Pieters* (Basel, Switzerland); Klaus Rajewsky* (Boston, USA); Rolf Zinkernagel* (Zürich, Switzerland) )

Local General Support: Hans-Joachim Wallny, Dieter Naeher, Randy Baron, Patricia Riegert, Regina Gerard, and more

CME Credits: Alan Tyndall and Colleageu (Basel, Switzerland)

Webpage: (Symposium 2011)

Registration: Wednesday, 8th June 2011, 12:00 –16:00 at Institue of Anatomy, University of Basel, Pestalozzistrasse 20, CH-4056 Basel

Dinner for early birds: Wednesday, 8th June 2011, at Restaurant Pizzeria Resslirytti, Theodorsgraben 42, beim Wettsteinplatz, Basel

Registration: Thursday, 9th June, 2011, 8:00-on, at Anatomie Institut, University of Basel, Pestalozzistrasse 20, CH-4056 Basel

Opening ceremony:
Date: Thursday, 9th June, 2011


Scientific program:
Date: Thursday, 9th June, 2011 am

Section A: Biology of the immune system

Chairperson: Marinus Lamers, Max Planck Institute for Immunobiology, Freiburg, Germany

TBA (Expansion of peripheral naturally occurring T regulatory cells by Fms-like typrosine kinase 3 ligand treatment)
Antonius Rolink, University of Basel, Basel, Switzerland


iNKT cells at the interface between innate and adaptive immunity
Mariolina Salio, John Radcliffe Hospital, Oxford, UK

Coffee break

Transcriptional regulation of plasma cell differentiation
Olli Lassila, University of Turku, Turku, Finland

RNA metabolism and Antibody Affinity maturation
Nobuo Sakaguchi, Kumamoto University, Kumamoto, Japan

Lunch break 11:55-13:00
Meet the Experts lunch by junior investigators and students

Date: Thursday 9th June 2011, pm
Continue Section A: Biology of the immune system
Section B: Beyond immune system
Chairperson: Olli Lassila, University of Turku, Turku, Finland

Biophysical studies of MHC class I molecules
Andreas Ziegler, Charite, Berlin, Germany

Inferring the primordial MHC and antigen receptor loci

Martin Flajnik, University of Maryland, Baltimore, USA

Moving targets: Phenotypic instability of a tet-off-SV40 Tag immortalized mouse ectodermal progenitor cell line
Una Chen, ISPI e.V. Giessen, Germany

Coffee break

Notch signaling controlled by histone methylation
Tilman Borggrefe, Max-Planck-Institute of Immunobiology & Epigenetics, Freiburg, Germany

Complex Systems - A Personal Journey from Research to Application
Charles Sidman, Bar Harbor, USA

Last minute speakers

17:00- 23:00 Social Program: Basel Tourist office announcement,
Please make your own reservation for concert or other social program in advance.

Dinner: Thursday, 9th June, 2011, of your own choice
Late evening drink at Kunsthalle, 21:00 onward
Date: Friday, 10th June, 2011, am

Section C: Immune response to self and to invader:
Autoimmune diseases:
Chairperson: Antonio Lanzavecchia, Institute for Research in Biomedicine, Bellinzona, Switzerland

Prevention of type 1 diabetes by Treg vaccination with an insulin mimetope
Harald von Boehmer, Harvard University, Boston, USA

Retroelements in the etiology of autoimmune disease
Matthias Wabl, University of California at San Francisco, California, USA

Human blood monocytes: disguised modulators of IL-17+ T cell responses
Elisabetta Padovan, Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal

Coffee Break

Deletion of CD44 variant isoforms limits EAE by control of CD4hi memory T cells
Ulla Günthert, University of Basel, Basel, Switzerland

Adult stem cells in the treatment of autoimmune disease
Alan Tyndall, Rheumatology, University Hospital & Felix-Platter Spital, Basel, Switzerland

Lunch break

Meet the Experts lunch by junior investigators and students

Date: Friday, 10th June 2011, pm
Chairperson: Federica Sallusto, Institute for Research in Biomedicine, Bellinzona, Switzerland

Cancer immunosurveillance by CD4+ T cells
Bjarne Bogen, Oslo University Hospital, Oslo, Norway

The plasma cell survival niche
Claudia Berek, DRFZ, Berlin, Germany

A new pathway to control IgE synthesis
Rolf Jessberger, Dresden, Germany

Coffee break

Section D: Infection, Inflammation and Immunity:
Chairperson: Hans-George Rammensee**, Tübingen, Germany;
Co-Chairperson: Lucia Mori*, University of Basel, Switzerland

Chromatin- dependent regulation of inflammatory gene expression
Dominic van Essen, Max Planck Institute for Immunobiology, Freiburg, Germany

Immunology and the safety of modern biotherapeutics
Harald Kropshofer, Hoffmann-La Roche AG, Basel, Switzerland

Turning Immunology into Pharmaceuticals
Donald Gerson, PnuVax, Inc, Ontario, Canada

Preparing for Public Education

Public Education on “Immunity and diseases”: (will be announced in local newspapers)

by speakers and participants of the symposium. The program will be announced locally.

END of scientific section

Bii-at-40 celebration program including:
Dinner: Friday, 10th June, 2011, 19:00 (Restaurant Löwenzorn, under BII at 40)

Further information: (Symposium 2011)

Registration Form Immunology Symposium Basel (ISB) 2011
for “Immune Responses and Autoimmunity“

can be viewed and downloaded under "Registration ISB 2011"

released: 19.12.2010, updated, 11.01.2011, 10.02.2011, 05.05.2011, 09.05.2011, 17.05.2011, 01.06.2011, 03.06.2011

Directions to Institute of Anatomy at Pestalozzistrasse:

- From EuroAirport:
Take bus no. 50 to SBB railwaystation, riding time is 19 min, then take bus no. 30 in direction
Badischer Bahnhof, leave at station "Frauenspital".

- From Badischer Bahnhof:
Take bus no. 30 and leave at station "Frauenspital".

-From SBB:
Take the bus no. 30 and leave at station "Frauenspital".